Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep543 | General Endocrinology | ECE2020

Vasoinhibin dimerization and measurement in human sera with a new vasoinhibin elisa

Triebel Jakob , Müller Nils , Ebnet Johannes , Neugebauer Leon , Harris David , Friedrich Christin , Markl-Hahn Hülya , Pablo Robles Juan , Zamora Magdalena , Martínez de la Escalera Gonzalo , Clapp Carmen , Bertsch Thomas

Vasoinhibin, historically also known as 16K PRL, is a peptide hormone with antiangiogenic, antivasodilatatory, and antivasopermeability effects generated by proteolytic cleavage of prolactin (PRL). The discovery of its role in diabetic retinopathy and peripartum cardiomyopathy led to the development of new pharmacological treatments and their evaluation in clinical interventional trials (ClinicalTrials.gov Identifier: NCT03161652 and NCT00998556). Recent insights into the func...